Flow Map for Hydrodynamics and Suspension Behavior in a Continuous Archimedes Tube Crystallizer

The Archimedes Tube Crystallizer (ATC) is a small-scale coiled tubular crystallizer operated with air-segmented flow. As individual liquid segments are moved through the apparatus by rotation, ATC operates as pump. Thus, overcomes pressure drop limitations of other continuous crystallizers, allowing for longer residence times and crystal growth phases. Understanding phenomena basis well-designed crystallization process, especially applications in pharmaceutical fine chemical industry. Hydrodynamics suspension behavior, example, affect agglomeration, breakage, attrition, ultimately blockage. In practice, however, it time-consuming to investigate these experimentally each new material system. this contribution, flow map developed five steps combination experiments, CFD simulations, dimensionless numbers. Accordingly, operating parameters can be specified depending on design system used, where behavior suitable high-quality crystalline products.